PMN对链球菌组蛋白样蛋白释放的影响  

Effect of Human PMN on the Streptococcal Histone-Like Protein Release

作　　者：张力平[1] 张红春[1] 靖学芳[1] 沈海中[1] 平国铃[1] 李郁英[1] 

机构地区：[1]首都医科大学微生物学教研室

出　　处：《首都医科大学学报》2003年第3期228-230,共3页Journal of Capital Medical University

基　　金：北京市自然科学基金资助项目 (7992 0 0 3 )

摘　　要：为观察人多形核白细胞 (PMN)对链球菌组蛋白样蛋白 (HlpA)释放的影响 ,将PMN与链球菌以一定比例共同作用后取上清液做免疫印迹试验。发现与抗HlpA抗体特异性结合的蛋白条带。提示PMN作用于链球菌后 。The objective of the study was to evaluate the effect of human PMN on Streptococcus HlpA release. Streptococcus was cultured with human PMN in different proportions and Western Blot was done to measure HlpA in the culture supernatant. There was one protein band combined specifically with anti-HlpA on Western Blot. The result indicates HlpA could be released from Streptococcus after being treated with human PMN, which is more than spontaneous release.

关 键 词：PMN 链球菌组蛋白样蛋白 HLpA 人多形核白细胞 免疫印迹试验 

分 类 号：R378.12[医药卫生—病原生物学] Q51[医药卫生—基础医学]