2-(1-咪唑基)乙酸的新法合成  

Synthesis of 2-(1-Imidazolyl)acetic Acid

作　　者：郑志兵[1] 谢云德[1] 李松[1] 

机构地区：[1]军事医学科学院毒物药物研究所,北京100850

出　　处：《中国医药工业杂志》2003年第10期494-494,共1页Chinese Journal of Pharmaceuticals

基　　金：国家自然科学基金 ( 3 0 0 80 0 0 3 )

摘　　要：Imidazolyl)acetic acid was prepared from imidazole by alkylation with ethyl chloroacetate and hydrolysis in one pot with an overall yield of 71.9%.Imidazolyl)acetic acid was prepared from imidazole by alkylation with ethyl chloroacetate and hydrolysis in one pot with an overall yield of 71.9%.

关 键 词：唑来膦酸 治疗 肿瘤 1-咪唑基 2-乙酸 乙酸乙酯 高血钙症 恶性骨转移瘤 2-(1-咪唑基)乙酸 合成 

分 类 号：R97[医药卫生—药品] R914.5[医药卫生—药学]