小儿健脾消食口服液挥发油提取工艺研究  

Study of the extraction technique of volatile oil from Chinese herbs for manufacturing Xiaoerjianpixiaoshi oral solution

作　　者：周本杰[1] 郭谦[2] 

机构地区：[1]第一军医大学珠江医院药剂科,广东广州510282 [2]广州军区直属第一门诊部药局,广东广州510080

出　　处：《第一军医大学学报》2003年第10期1104-1105,共2页Journal of First Military Medical University

基　　金：广东省中医药局2002年资助课题~~

摘　　要：目的确定小儿健脾消食口服液挥发油提取的最佳工艺。方法以两种水蒸汽蒸馏工艺提取含挥发油药材,紫外分光光度仪测蒸馏液中挥发油的含量,采用Exponential曲线回归分析法建立挥发油馏出规律的数学模型。结果水蒸汽蒸馏直接提取挥发油效果更佳,挥发油馏出量按指数函数规律递减,收集2倍量蒸馏液即可收集61.64%的挥发油。结论加8倍量水、浸泡0.5 h、加热水蒸汽蒸馏、收集蒸馏液2倍量为最佳挥发油提取工艺。Objective To determine the optimal extracting technique for the volatile oil from the Chinese herbs for manufacturing Xiaoerjianpixiaoshi oral solution. Methods Two steam distillation processes were carried out to extract the volatile oil from three Chinese herbs. UV-spectrophotometry method was used to determine the oil content in the distillate, and the mathematical model was established according to volatile oil distillation process by exponential curve regression analysis. Result Direct extraction of the oil by means of steam distillation process was more workable, and the decrement of oil content conformed well with the exponential model. Collection of 2 volumes of the distillate resulted in the yield of volatile oil of 61.64%. Conclusion The optimal extraction of the volatile oil can be resulted from immersion of the drugs in 8 volumes of water for 0.5 h and collection of 2 volumes of the distillate.

关 键 词：小儿健脾消食口服液 挥发油 提取工艺 中药 紫外分光光度仪 

分 类 号：TQ461[化学工程—制药化工]