囊性肺纤维化同种异体肺移植1例报告  

Lung transplantation for treatment of pulmonary cystic fibrosis:report of one case

作　　者：陈钢[1] 杨锡耀[1] 蔡瑞君[1] 黄志勇[1] 穆峰[1] 吴旭[1] 孟辉[1] 

机构地区：[1]第一军医大学南方医院胸外科,广东广州510515

出　　处：《第一军医大学学报》2003年第10期1115-1116,共2页Journal of First Military Medical University

摘　　要：为1例17岁女性严重囊性肺纤维化患者行右侧单肺移植,术中未用体外循环,供肺采用冷UW液灌注,冷缺血时间280 min。术后18 h停用呼吸机,第4天下地活动。术后免疫抑制剂选用甲基强的松龙冲击治疗后再用“新三联”(FK 506,骁悉,强的松)维持后续治疗。患者术后恢复顺利,复查肺功能基本正常,动脉血气分析显示较术前明显改善。术后第1个月未出现严重排异反应,目前存活状况良好。A right single lung transplantation was performed in a 17-year-old female patient with end-stage cystoid pulmonary fibrosis and without cardiopulmonary bypass in June 2003. The donor lung was perfused with cold UW solution with a cold ischemic time of 280 min. The patient weaned from ventilator on the next day of operation (18 h later) and was able to walk at the fourth day postoperatively. Immunosuppression included methylprednisolone used before FK 506, mycophenolate mofetil and prednisone dosed after operation. The patient remains well a month after operation with significant improvement of the lung function and enjoys normal life.

关 键 词：囊性肺纤维化 同种异体 肺移植 甲基强的松龙 冲击疗法 

分 类 号：R655.3[医药卫生—外科学]