混合配体配合物[Pd(bpy)(L-asp)]·3.5H_2O的晶体结构及其稳定性研究  

Studies on the Crystal Structure and Stability in Solution of Mixed Ligand Complex of Palladium(Ⅱ) with 2,2′-Bipyridine and L-Aspartic Acid

作　　者：高恩君[1] 张丹[1] 刘祁涛[2] 

机构地区：[1]沈阳化工学院配位化学研究室 [2]辽宁大学化学科学与工程学院沈阳110036东北师范大学化学学院长春130024

出　　处：《化学学报》2003年第11期1834-1838,共5页Acta Chimica Sinica

基　　金：辽宁省自然科学基金 (No.2 0 0 2 2 0 1 8);沈阳化工学院拔尖人才基金资助项目

摘　　要：合成了混合配体配合物单晶 [Pd(bpy) (L asp) ]·3 .5H2 O (bpy =2 ,2′ 联吡啶 ,L asp2 -=L 天冬氨酸根 ) .用红外光谱和元素分析对配合物的成键及组成进行了表征 .用X射线单晶衍射仪 (CCD)测定了配合物的结构 ,晶体属四方晶系 ,为P4( 1) 2 ( 1) 2空间群 .配合物为平面四边形结构 ,分子内存在氢键作用 ,其晶胞靠氢键和芳环堆砌等弱相互作用力形成 .用电位滴定法测定了配合物稳定常数lgK[Pd2 + +bpy +L asp2 Pd(bpy) (L asp) ]、表征常数ΔlgK[Pd(bpy) 2 + Pd(L asp)Pd(bpy) (L asp) +Pd2 + ]和lgX[Pd(bpy) 2 + 2 +Pd(L asp) 2 -2 2Pd(bpy) (L asp) ] ,各常数均大于相应的统计期望值 ,从分子内dThe mixed ligand complex Studies on the Crystal Structure and Stability in Solution of Mixed Ligand Complex of Palladium(Ⅱ) with 2,2′ Bipyridine and L Aspartic Acid $$$$ GAO, En Jun , a,c ZHANG, Dan a LIU, Qi Tao b,c ( a Coordination Chemistry Section, Shenyang Institute of Chemical Technology, Shenyang 110142) ( b College of Chemistry, Liaoning University, Shenyang 110036) ( c College of Chemistry, Northeast Normal University, Changchun 130024) Abstract The mixed ligand complex [Pd(bpy)( L asp)·3.5H 2O (bpy=2,2′ bipyridine, L asp= L aspartic acid) (1) has been synthesized and characterized by IR spectra, elemental analysis and electroconductivity. The molecular structure and the packing of 1 have been determined by single crystal X ray structure analysis. The results show that the Pd(Ⅱ) in 1 has a square planar coordination geometry and the molecules of 1 are assembled via hydrogen bond and intermolecular aromatic ring stacking. The crystal of 1 belongs to tetragonal, space group P 4(1)2(1)2, a=b =1 5979(3) nm, c =1 3749(5) nm, Z =8, V =3.5105(15) nm 3. The stability of the mixed ligand complex was determined by the pH potentiometric titration technique in water at 37 ℃ and 0 10 ionic strength (NaCl). The results show that the complex is quite stable. The higher scale values of relative stability Δlg K and lg X demonstrate that the complex possesses enhanced stability. The reasons that lead to these results were discussed in terms of π electron back donation and electroneutralization.

关 键 词：混合配体配合物 [Pd(bpy)(L-asp)]·3.5H2O 晶体结构 稳定性 钯配合物 氢键 芳环堆砌 抗肿瘤活性 

分 类 号：O641.4[理学—物理化学]