气相色谱法测定血浆中毒鼠强  

Determination of tetramine in plasma by gas chromatography

作　　者：陈忠辉[1] 葛晓伟[1] 郭君[1] 鲁雁飞[1] 李晓华[1] 

机构地区：[1]中国疾病预防控制中心职业卫生与中毒控制所,北京100050

出　　处：《卫生研究》2003年第5期493-494,共2页Journal of Hygiene Research

摘　　要：液 -液萃取、毛细管气相色谱 氮磷检测器法测定血浆中毒鼠强。标准曲线线性范围 0 1～ 5 μg ml。三倍噪声的检出限为 1 5pg ,定量限为 10ng ml血 ,高、中、低三个浓度的回收率分别为 96 0 %、10 7 0 %和10 6 8%、批内精密度为 9 6 %、9 8%和 7 8% (RSD)、批间精密度为 6 6 %、8 5 %和 6 2 % (RSD)。样品在 -4℃冰箱保存可稳定A method was developed to measure the tetramine in plasma by liquid-liquid extraction and GC-NPD with the limit of detection(LOD) 1.5pg and the limit of quantity 10ng/ml. The linear range was 0.1-5μg/ml with a correlation coefficient of 0.999. Recoveries for three concentrations of tetramine were 96.0%,107.0%,106.8%. The intra-day precision were 9.6%,9.8%,7.8%, the inter-day precision were 6.6%,8.5%,6.2%. Tetramine in plasma was stable up to 5months at -4℃.

关 键 词：毒鼠强 血浆 气相色谱法 氮磷检测器 

分 类 号：R595.4[医药卫生—内科学] S482.55[医药卫生—临床医学]