脂代谢异常与老年糖尿病并发冠心病的关系  

THE RELATIONSHIP BETWEEN THE LIPID LEVEL AND TYPE 2 DIABETES WITH CORONARY DISEASE IN THE ELDERLY

作　　者：李晓红[1] 王德全[2] 张秀英 

机构地区：[1]德州市人民医院,德州市253014 [2]山东大学齐鲁医院 [3]济南军区90医院

出　　处：《滨州医学院学报》2003年第6期432-433,共2页Journal of Binzhou Medical University

摘　　要：目的 :应用回顾性病例对照研究方法 ,探讨血脂异常与老年糖尿病并发冠心病的关系。方法 :随机选择无血缘关系的 2型糖尿病 ( DM2 )患者 1 0 2例 ,根据是否并发冠心病进一步分为糖尿病并发冠心病组及糖尿病非冠心病组。健康对照组 5 2例 ,均无血缘关系 ,无糖尿病、冠心病史。记录受试者空腹血糖 ( FBG)以及血清总胆固醇 ( TC)、甘油三脂 ( TG)、高密度脂蛋白胆固醇 ( HDLC)等脂质代谢指标。低密度脂蛋白胆固醇 ( LDLC)据 Freidewaild公式计算 ( LDLC=TC- HDLC- TG/2 .2 )。用 SPSS9.0软件处理 ,检验水平α±0 .0 5。结果 :糖尿病组 TC、TG、LDLC均值均显著低于对照组 ,而 HDLC均值显著低于糖尿病非冠心病组 ;lo-gistic逐步回归分析示 TC、LDLC进入回归方程。结论 :DM2患者伴有明显的脂代谢紊乱 ;TC。Objective:To investigate the relationship between the lipid level and type 2 diabetes with coronary disease elderly.Methods:102 cases of type 2 diabetes elderly were diagnosed according to IDF WPR criteria who were complicated by coronary heart disease(CHD).52 cases were healthy controls.The clinical index of all subjects were recorded.Results:The levels of TC,TG and LDLC in DM2 were significantly higher than those in the normal controls ( P <0 05 respectively).The levels of TC and LDLC in DM2 with CHD elderly were significantly higher than those in DM2 with no CHD.Conclusion:The levels of TC and LDLC are risk factors of DM2 complicated with CHD elderly.

关 键 词：老年糖尿病 血脂水平 冠心病 

分 类 号：R715[医药卫生—妇产科学]