固体超强酸催化合成氯乙酸乙酯新工艺研究  

Stady on new process for catalytic synthesis of ethyl chloroacetate with solid super strong acid

作　　者：黄慧[1] 陈理[1] 柳金章[1] 徐海燕[1] 李嘉珞[1] 

机构地区：[1]大连大学化学与化学工程系,辽宁大连116622

出　　处：《应用化工》2003年第5期36-38,共3页Applied Chemical Industry

摘　　要：以固体超强酸为催化剂,取消带水剂,采用多次加入乙醇的方法合成氯乙酸乙酯,酯化率达98 8%,经放大实验,结果稳定。最佳酯化条件为:催化剂用量为反应物总质量的1 2%,酸醇摩尔比1 0∶6 6,反应时间5～6h,乙醇按预定加入量及加入模式分多次加入。Solid super acid was used as the catalyst for the synthesis of ethyl chloroacetate,using the methods of nonwater carring agent and multiple adding of alcohol.The total yield was up to 98.8%,which was maintained almost at the same level during the scalingup of the experiments. The results showed that the optimum conditons of esterification are as follows:the amount of solid super acid catalyst is 1.2% of total mass of reactants,the molar ratio of acid to alcohol is 1.0∶6.6,the reaction time is 5～6 h,adding alcohol in multiple time with the reaction proceeding.

关 键 词：氯乙酸乙酯 固体超强酸催化剂 新工艺 

分 类 号：O623.64[理学—有机化学]