三苯氧胺治疗50例子宫内膜异位症  

TAMOXIFEN TREATMENT FOR ENDOMETRIOSIS:A REPORT OF 50 CASES

作　　者：周琴慧[1] 酆豫增[1] 

机构地区：[1]上海市第一人民医院妇产科

出　　处：《上海医学》1992年第4期205-207,共3页Shanghai Medical Journal

摘　　要：对三苯氧胺治疗经腹腔镜或病理检查确诊的50例子宫内膜异位症进行了分析。从月经第5天开始服药,每次10mg,每天2次,共20天。74％患者服用6～10个周期。治疗后痛经和月经过多明显好转或消失各为89.74％(35/39例)和93.75％(15/16例)。体征明显改善57.5％(23/40例)。纠正受孕率为27.7％。该药能明显控制痛经,不抑制排卵,副作用小。Fifty patients with endometriosis confirmed by laparoscopic or pathologic examination were treated with tamoxifen, which was started from the fifth menstrual day at a dose of 10mg bid for 20 days. Seventy-four percent of the patients were treated for 6-10 courses. Dysmenorrhea, menorrhagia and pelvic signs were improved or disappeared respectively in 89.7% (35/39), 93.75% (115/16) and 57.5% (23/40) of the patients. It is preliminarily concluded that 1. tamoxifen is effective in the control of symptoms of endometriosis; 2. ovulation is not inhibited, and thus tamoxifen is more appropriate for infertile patients; and 3. it has less side effects and is less expensive.

关 键 词：三苯氧胺 子宫内膜异位症 

分 类 号：R711.710.5[医药卫生—妇产科学]