各期孕妇及新生儿巨细胞病毒感染的调查  

INVESTIGATION OF CYTOMEGALOVIRUS INFECTION IN PREONANT WOMEN AND THEIR NEONATES

作　　者：朱丹红[1] 徐桂林[1] 陈淑云[1] 陈嘉华[1] 丁健青[1] 

机构地区：[1]上海第二医科大学微生物学教研室

出　　处：《上海医学》1992年第7期399-401,共3页Shanghai Medical Journal

摘　　要：对212名早中期孕妇和90名晚期孕妇的血清及其新生儿脐血,检测巨细胞病毒(CMV)特异性IgG和IgM抗体,结果IgG阳性率高达94.4％。IgM阳性率,早、中期孕妇为2.3％,晚期孕妇为7.8％,后者明显高于前者(P<0.05)。新生儿IgM阳性率为3.3％,母子均为阳性者占2.2％。提示母亲CMV活动期感染与新生儿的先天感染有着密切关系。Specific serum IgG and IgM antibodies against cytomegalovirus (CMV-IgG, CMV-IgM) in 212 early, middle pregnant women and 90 late stage pregnant women, and in 90 umbilical cord serum samples of their neonates were examined. The results showed that the positive rate of specific CMV-IgG was 94.4%, and that of CMV-IgM in early, middle pregnant women and late pregnant women was 2.3% and 7.8% respectively. The latter was higher than the former (P<0.05). The positive rate of CMV-IgM was 3.3% in neonates and 2.2% in both mother and baby. It suggested that the active infection of mother was closely related to the congenital infection of neonate.

关 键 词：巨细胞病毒 孕妇 新生儿 

分 类 号：R722.139[医药卫生—儿科]