尿激酶治疗颅内血肿对凝血机制的影响  

The Effect of Blood Coagulation Mechanism on the Treament of Intracranial Hematoma with Urokinase

作　　者：李创忠[1] 王今才[1] 李琛[1] 王玉国[2] 

机构地区：[1]解放军第230医院神经外科,辽宁丹东118000 [2]解放军第230医院检验科,辽宁丹东118000

出　　处：《临床军医杂志》2003年第5期24-25,共2页Clinical Journal of Medical Officers

摘　　要：目的 探讨尿激酶冲洗治疗颅内血肿对凝血机制的影响。方法 检测分析33例应用尿激酶治疗的颅内血肿患者的术前、术中、术后凝血酶原时间(PT)、国际标准差比值(INR)、激活凝血酶原时间(APTT)及纤维蛋白酶原含量(FIB)。结果 术中、术后凝血机制无明显改变,经统计学检验无明显差异。结论 尿激酶冲洗治疗颅内血肿疗效确切、损伤小,且不会破坏凝血机制。Objective To explore the effect of blood coagulation mechanism on the treatment of intracranial hematoma with uroki-nase. Methods Take notes the result of PT.INR,APTT and FIB before treatment for 33 cases,and then pour urokinaae that about 8 × 105 - 106 units into hematoma, take notes the result of inter and after treatments. Analyse the data -with statistics. Results It hasntclear difference between before and after treatment. Comclusion The treatment can' t cause change of blood coagulation mech-

关 键 词：颅内血肿 尿激酶 凝血机制 凝血酶原时间 激活凝血酶原时间 纤维蛋白酶原含量 

分 类 号：R651.15[医药卫生—外科学] R977.3[医药卫生—临床医学]