肺炎支原体感染与小儿哮喘的关系  

Relationship between the mycoplasma pneumonia infections and children with bronchial asthma

作　　者：李江[1] 

机构地区：[1]广西壮族自治区妇幼保健院,南宁530003

出　　处：《医学文选》2003年第5期635-636,共2页Anthology of Medicine

摘　　要：目的　探讨肺炎支原体 (MP)感染与哮喘发作的关系 ,以及 MP感染的治疗方法。方法　哮喘发作期患儿 1 3 3例 ,按是否伴有感染分为感染组和非感染组 ,分别采用 ELISA法测定静脉血 MP- Ig M抗体 ,观察大环内酯类抗生素疗效。结果　感染组患儿 MP- Ig M阳性率为 1 8.8%(1 6 /85 ) ,非感染组阳性率为2 .0 %(1 /4 8) ,哮喘组 MP- Ig M阳性率非常明显高于对照组 (P <0 .0 0 1 )。MP- Ig M阳性的哮喘患儿予大环内酯类抗生素治疗后哮喘明显缓解。结论　MP感染与哮喘有密切的关系 ,大环内酯类抗生素疗效确切。Objective To explore the relationship between the mycoplasma pneumonia infections and children with bronchial asthma and treatment.Methods Of the 135 cases were in the acute episode,85 cases with infections,48 cases with non-infections.Serum MP-IgM level was assayed with ELISA method.The effect of the macrolides was observed.Results Positive MP-IgM in the cases with infections was found in 16 cases (18.8%),of which 1 cases (2.0%) was seen in non-infection.the numbers of infection was obviously higher than non-infection (P<0.001).After being treated with the macrolides,the children of MP-IgM(+) obviously remit.Conclusions Children with MP infection have close relationship with the bronchial asthma.Treating with the macrolides has the exact effect.

关 键 词：哮喘 肺炎支原体 肺炎支原体特异性抗体 大环内酯类抗生素 

分 类 号：R725.6[医药卫生—儿科]