孤立性房颤的临床特征分析  

The analysis of clinical features of lone atrial fibrillation

作　　者：王淑敏[1] 陈凤荣[1] 张萍[2] 

机构地区：[1]北京大学第三医院心内科,100083 [2]北京大学人民医院心内科

出　　处：《中国药物与临床》2003年第5期380-382,共3页Chinese Remedies & Clinics

摘　　要：目的　分析孤立性房颤 (LAF)临床特征对其预后及结局的影响。方法　共收集LAF 10 4例 ,高血压房颤 (HPAF) 4 9例 ,以HPAF组为对照 ,采用单因素的 χ2 检验和多因素的逐步Logistic回归方法 ,对LFA的性别、年龄、并发症、家族史等临床特征及超声心动图指标进行分析。结果　与HPAF组相比 ,LAF组左房增大患者检出率较低 (P =0 0 4 1) ,低龄发病患者较多 (P =0 0 2 9) ;无论在LAF组 (P =0 0 16 )还是在HPAF组 (P =0 0 4 7) ,持续性房颤患者并发症检出率均较高 ;左房增大与房颤持续性、左室舒张末内径及高血压呈正相关。结论　在LFA患者 ,不同的临床特征具有不同的自然病程及结局 。Objective The study was conducted to investigate the association between clinical features of lone atrial fibrillation (LAF) and its outcomes. Methods One hundred and four patients with LAF and 49 patients with atrial fibrillation and hypertension (HPAF)were enrolled.Clinical data of all patients were collected.Results By univariate analysis,patients with left atrial dilation were less in LAF group than in HPAF group,but the number of early onset patients was larger in LAF group.More complications were found in patients with persistent atrial fibrillation than in patients with paroxysmal atrial fibrillation in both groups.By logistic regression analysis,left atrial dilation in patients with atrial fibrillation was positively related with hypertension,left ventricle dilation and persistent atrial fibrillation.Conclusion Outcomes of patients with lone atrial fibrillation varied with clinical features,and left atrial dilation was an impotant predictor of prognosis.

关 键 词：孤立性房颤 临床特征 预后 性别 年龄 并发症 

分 类 号：R541.75[医药卫生—心血管疾病]