合肥市病毒性肝炎血清流行病学调查  

Seroepidemiological study of viral hepatitis in Heifei district

作　　者：刘怀珠[1] 刘旭祥[1] 陆群[1] 张庆枝[1] 刘先敏[1] 徐凤霓[1] 王海[1] 

机构地区：[1]合肥市疾病预防控制中心,安徽合肥230061

出　　处：《疾病控制杂志》2003年第5期433-435,共3页Chinese Journal of Disease Control and Prevention

摘　　要：目的　了解合肥市自然人群病毒性肝炎流行特征。方法　采用多阶段分层整群抽样法 ,选取合肥市 7个调查点的 75 9户家庭 1～ 5 9a居民 ,抽取血样本 186 9份 ,采用 EL ISA法检测抗 -HAV、HBs Ag、抗 - HBc、HBe Ag、抗 - HCV,RIA法检测抗 - HBs。结果　人群各指标阳性率抗 - HAV为 77.87%、抗 - HCV为 0 .16 %、HBs Ag 8.2 5 %、抗 - HBs5 3.12 %、抗 - HBc 41.6 6 %。 10 a以下儿童抗 - HAV阳性率低 ,HBs Ag阳性率儿童峰消失。接种乙肝疫苗人群 HBs Ag阳性率低于未接种者 ,差异有显著性。结论　预防甲、乙型肝炎病毒感染最有效的措施是接种甲、乙型肝炎疫苗。Objective To understand the infectious status of hepatitis virus among nature population in Hefei city. Methods 1 869 individuals aged 1～59 among 759 families were selected from 7 regions in Hefei city by stratified random cluster sampling. Anti-HAV, HBsAg, Anti-HBc, HBeAg, Anti-HCV and Anti-HDV was detected by enzyme immunoassay (EIA); Anti-HBs was detected by radio immunoassay (RIA). Results The standardized positive rates of HAV, HCV, HBsAg and Anti-HBs were 77.87%, 70.86%, 0.16%, 8.25%, 53.12% and 41.66%. Prevalence rate of HAV was low among children under 10 years old. The positive rate of HBsAg was decreasing among children. The positive rate of HBsAg of people who had been inoculated was lower than that who had not been inoculated. Conclusions Vaccination is an efficient way to prevent the infection of HAV and HBV.

关 键 词：病毒性肝炎 血清流行病学 疫苗 合肥市 

分 类 号：R512.6[医药卫生—内科学]