中西医结合治疗49例SARS临床对照研究  

Controlled Clinical study on 49 Patients of SARS Treated by Integrative Chinese and Western Medicine

作　　者：张瑞麟[1] 焦强[1] 王保国[2] 冯力民[2] 王飙[1] 王海箭[1] 罗燕楠[1] 剡雄[1] 沈红强[1] 马英明[1] 熊云[1] 陈卫衡[1] 马达[1] 程桯[1] 周卫[1] 

机构地区：[1]中国中医研究院望京医院驻朝阳妇幼保健院SARS定点医疗队,北京100102 [2]北京天坛医院驻朝阳妇幼保健院SARS定点医疗队

出　　处：《中国中西医结合杂志》2003年第9期654-657,共4页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的 :评价中西医结合治疗SARS的疗效。方法 :采用平行对照研究 ,完成评估病例共 4 9例 ,其中对照组 2 9例 ,采用卫生部《传染性非典型肺炎推荐治疗方案》 ,应用利巴韦林、左旋氧氟沙星、阿奇霉素、糖皮质激素 (甲基强的松龙 )等药物 ;治疗组 2 0例 ,在对照组治疗的基础上 ,采用了科技部“防治SARS特别科技行动”中西医结合治疗SARS的方案。结果 :(1)症状改善所需时间 ,治疗组为 5 10天 ,对照组为 7 6 2天 ,两组比较差异有显著性 (P <0 0 5 )。 (2 )激素减量前使用的总量和天数 ,两组比较差异无显著性 (P >0 0 5 )。(3)激素减量后使用的总量和天数两组比较差异有显著性 (P <0 0 5 )。 (4 )改善外周血白细胞总数及淋巴细胞绝对值和胸片片状影吸收的时间 ,两组比较差异无显著性 (P >0 0 5 )。结论 :中西医结合治疗SARS ,在改善临床症状、减少激素用量和缩短疗程上 ,比单纯西医治疗有明显的优势。Objective: To evaluate the efficacy of Integrative Chinese and western medicine (ICWM) in treating SARS. Methods: By controlled paralled design, 49 patients of SARS were studied, they were divided into the control group (n=29) and the ICWM group (n=20). The former was treated according to the 'Recommended Program for Treatment of SARS'provided by Health Ministry, by administering of such drugs as Ribavirin, Levofloxacin, Thymopentin, Azithromycin, etc, the latter was treated with the ICWM protocol for SARS of 'Special Technological Action to Prevent and Treat SARS'provided by Science and Technology Ministry. Results: (1)The time for improving symptom in the ICWM group was 5.10 days and that in the control group was 7.62 days, the difference between them was significant (P<0 05); (2) The days and amount for use hormone before subtract in the two group were similar, with insignificant difference (P>0 05); (3) The days and amount for use hormone after subtract in the two groups were significantly different (P<0 05); (4) The time for improving peripheral WBC count and absolute value of lymphocyte, as well as for absorption time of shadow in chest film were not different singnificantly between the two groups (P>0 05). Conclusion: In treating SARS, ICWM was superior to the treatment with western medicine alone in aspects of improving clinical symptom, promoting recovery of immune function and absorption of lung inflammation, decreasing the dosage of hormone used and shortening the therapeutic course.

关 键 词：中西医结合治疗 SARS 对照研究 激素 非典型肺炎 

分 类 号：R511.9[医药卫生—内科学]