细胞色素C引起心磷脂的还原  

Reduction of Cardiolipin upon Interaction with Ferrocytochr-ome C

作　　者：程昆蓉 程伯基[1] 宋慧芳[2] 乔梁[2] 王动[2] 倪雪梅[2] 林克椿[1] 

机构地区：[1]北京医科大学生物物理教研室,北京100083 [2]北京医科大学分析计算中心,北京100083

出　　处：《生物化学杂志》1992年第5期574-577,共4页

基　　金：国家自然科学基金

摘　　要：本工作采用FT-IR和NMR技术,研究了心磷脂(CL)与还原态细胞色素C作用后其脂肪酸链中双键数目的变化。发现伴随细胞色素C的氧化,CL双键被部分还原为单键,提示CL可能直接参与吸呼链的电子传递。It has been reported that cardiolipin (CL) could oxidize ferrocytochrome c.In this work, change of double bonds in acyl chain of CL in reaction with ferrocytochrome C was studied by FT-IR and NMR techniques.It was observed that the number of double bond in C was decreased upon interaction with ferrocytochrome c.The role of CL in electron transfer between cytochrome c and cytochrome c oxidase is discussed.

关 键 词：心磷脂 细胞色素C 氧化还原 

分 类 号：Q545[生物学—生物化学]