老年2型糖尿病合并脑梗死的临床特点探讨  

The clinical features of type 2 diabetes mellitus complicated with cerebral infarctin in elderly

作　　者：童慧[1] 宋文英[1] 马宾[1] 

机构地区：[1]安徽蚌埠医学院附属医院老年病科,233004

出　　处：《临床中老年保健》2001年第3期157-158,共2页

摘　　要：目的　探讨老年人 2型糖尿病合并脑梗死时的临床特点。方法　对 97例老年糖尿病合并脑梗死病人与 2 9例非老年 2型糖尿病合并脑梗死病人进行临床对照分析。结果　脑梗死发生时老年组病人空腹血糖、血胰岛素、胰岛素敏感指数、神经系统功能缺失评分分别为 11 15± 2 35mmol/L、12 73± 7 33IU/L、- 4 94± 0 5 5、2 6 49± 11 39;而非老年组分别为 13 88± 2 6 5mmol/L、9 49± 4 37IU/L、- 4 2 4± 0 5 7、2 0 5 3± 6 2 0 ;两者相比差异有显著意义 (P <0 0 5 )。头颅平扫显示非老年组病人多以基底节区多发性腔隙梗死为主 ,面积较小 ;而老年组梗死面积较大。老年组在应用降纤维蛋白药物后 ,纤维蛋白原下降幅度较非老年组大。结论　老年人 2型糖尿病并发脑梗死病情较重。早期严格控制血糖水平 ,治疗上慎用抗凝、溶栓、降纤维蛋白药物十分重要。Objective To investigate the clinical features of type 2 diabetes mellitus complicated with cerebral infarction in elderly.Methods The data of 97 aged type 2 diabetics complicated with cerebral infarction were compared with those of 29 cases of young and middle aged patients.Results The level of fasting blood glucose(FBG),Insulin(In),the index of insulin sensitivity(ISI),neurological functional deficit scales(NFDS) in the elderly group were 11.15±2.35mmol/L,12.73±7.33IU/L,-4.94±0.55,26.49±11.39;While in the non elderly group,those were 13.88±2.65mmol/L,9.49±4.37IU/L,-4.24±0.57,20.53±6.20,respectively,there were significant difference between the two groups(P<0.05).CT showed there were wider range of brain imaging abnormalities in elderly patients than in non elderly patients,there were much more adverse effection(such as cerebral hemorrhage) in senile patients than in non elder patients after antithrombotic therapy.Conclusion It is importart to control the level of plasma grucose,and to take cautious when antithrombotic therapy is operated for senile diabetics with cerebral infarction.

关 键 词：老年人 2型糖尿病 合并症 脑梗死 临床特点 

分 类 号：R587.1[医药卫生—内分泌] R743.33[医药卫生—内科学]