甾体避孕药不增加血栓栓塞性疾病危险(病例对照研究)  

Steroid Contraceptives Causing No Increase in Risk of Thromboembolism (Case-Control Study)

作　　者：瞿美秋 周维谨[1] 唐威[1] 张德玮 钱可久[1] 丁怀翌 宰春和 

机构地区：[1]上海市计划生育科学研究所

出　　处：《生殖与避孕》1992年第3期18-22,17,共5页Reproduction and Contraception

摘　　要：本文采用1:3病例对照研究方法,对甾体避孕药的使用与血栓栓塞性疾病(急性心肌梗塞、脑栓塞、脑血栓形成和深静脉血栓形成)间的关联进行多因素分析。结果提示在我国广泛应用的甾体避孕药(主要为国产Ⅰ号避孕药)并不增加血栓栓塞性疾病的危险性。用药和停药时间的长短与血栓栓塞性疾病的发生无关,并与高血压病之间亦不存在协同作用。A case-control study was made for the investigation of relationship between steroid contraceptives and diseases of thromboembolism (AMI, DVT, Cerebral embolism and Cerebral thrombosis). The analytical results by multiple conditional Logistic regression showed that the steroid contraceptives commonly applied in Shanghai (mainly Chinese Pill №1, made in China) did not increase the risk of thromboembolism. Duration of using contraceptives and interval from stopping the attack did not influence the risk of thromboembolism, nor showed any effect in coordination between steroid contraceptives and hypertension.

关 键 词：避孕药 血栓栓塞 

分 类 号：R979.21[医药卫生—药品]