高原高血压患者血清一氧化氮水平的变化及意义  

Changes Nitric Oxide Level and Importance in Patients with High Altitude Hypertension

作　　者：余军[1] 巴焕玲[1] 李诗东[1] 侯同川[1] 周建胜[1] 刘玉江[1] 符中明[1] 

机构地区：[1]解放军第41医院内科,西藏乃东856100

出　　处：《临床军医杂志》2003年第4期11-12,共2页Clinical Journal of Medical Officers

摘　　要：目的 观察高原高血压患者血清一氧化氮(NO)的水平及意义。方法 对39例高原高血压患者在应用卡托普利治疗前后进行一氧化氮含量的测定,并与20名高原健康自愿者进行比较。结果 高原高血压患者血清NO水平较正常对照组明显降低(P<0.01)。结论 高原高血压患者体内NO水平显著降低,表明NO水平的改变可能参与了高原高血压的发病过程。Objective To investigate the changes of nitric oxide (NO) level in serum and impboortance in patients with high altitude hypertension. Methods The NO level in seium was measured before and after treatment in the patents-group (39cases) , and 20 local healthy volunteers served as control. Results The NO level in serum was significantly fowr in the patients-group than tha of control-group ( P < 0.01 ). Conclusion The NO level in senun was significanly lower in the patients-group than that of control-group, which may participate the course of its pathogenesis.

关 键 词：高原高血压 一氧化氮 卡托普利 药物治疗 

分 类 号：R544.1[医药卫生—心血管疾病] R972.4[医药卫生—内科学]