应用随机双盲法观察苦碟子注射液治疗冠心病心绞痛的疗效  

THE EFFICACY OF“KU DIE Zl”INFUSION IN THE MANAGEMENT OF ANGINA PECTORIS WITH CORONARY HEART DISEASE

作　　者：李连广 董瑞祥 仲苏媛 朱惠贞 李明仪[2] 金国良[2] 王璞[2] 宋道岭[3] 柯若仪[3] 商锦坤 

机构地区：[1]204医院内科 [2]哈尔滨医科大学附属第二医院 [3]大连医学院附属医院 [4]锦州铁路中心医院

出　　处：《解放军医学杂志》1989年第1期30-32,共3页Medical Journal of Chinese People's Liberation Army

摘　　要：选择冠心病心绞痛312例随机分成3组治疗,以验证苦碟子的疗效。其中甲,乙二组为双盲对照。甲组110例用苦碟子注射液治疗。乙组104例用复方丹参注射液治疗。丙组98例用低分子右旋糖酐注射液治疗。其症状有效率甲、乙、丙三组分别为90.9％、86.5％和89.8％。三组间无显著差异。心电图有效率甲、乙、丙三组分别为51.8％、38.5％和61.2％。甲与乙,丙二组相比均无显著差异(P>0.05)。在苦碟子组治疗中仅1例大便稀溏。作者认为,苦碟子可以作为治疗冠心病心绞痛的有效药物。值得推广应用。To determine the efficacy of 'Ku Die Zi' infusion 312 patients were selected and randomized into three groups.Groups A and B compared in a double blind way.'Ku Die Zi' infusion was used in 110 patients of group A,and injection salviae miltiorrhizae composita in 104 patients of group B,and low-molecule Dextran infusion in 98 patients of group C.The rates of improvement of symptoms were 90.9%,86.6%,and 89.8%,respectively,in the three groups.The rates of improvement of ECG were 51.8%,38.5% and 61.2%,respectively.There was no significant difference between groups A and B and A and C (both P>0.05).One of the cases had loose stools during the treatment with 'Ku Die Zi' infusion.It was believed that 'Ku Die Zi' infusion was a valuable drug for further clinical trial.

关 键 词：冠心病 苦碟子 疗效观察 

分 类 号：R541.4[医药卫生—心血管疾病]