DOBUTAMINE MAGNETIC RESONANCE IMAGING PREDICTS CONTRACTILE RESERVE OF CHRONICALLY DYSFUNCTIONAL MYOCARDIUM: COMPARISON WITH FLUORINE-18 FLUORODEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY  

作　　者：赵世华 刘少忠 MarcJanier PierreCroisille JeanP.Roux DidierRevel 

机构地区：[1]LaboratoireCreatis-UMR-CNRS5515,HopitalCardiovasculaireetPneumologiqueLyon,France [2]DepartmentofRadiology,FuWaiCardiovascularHospital,CAMS＆PUMC,Bijing100037 [3]InternalMedicine,ChizhouHospital,AnhuiProvince

出　　处：《Chinese Medical Sciences Journal》2000年第1期29-34,共6页中国医学科学杂志（英文版）

摘　　要：This study sought to investigate whether low dose dobutamine MRI can detect residual myocardial viability in patients with chronic myocardial infarction and left ventricular dysfunction. Methods. Eleven patients with chronic myocardial infarction and left ventricular dysfunction were employed for identification of viable myocardium by cine MRI during dobutamine infusion. All patients underwent coronary angiography and left ventriculography, 18 FDG PET, MRI at rest and stress.The systolic wall thickening measured at rest and during stress was compared with the results of 18 FDG PET, respectively. Results. A significant difference of either dobutamine induced systolic wall thickening (SWth stress ) or dobutamine induced contractile reserve (ΔSWth= SWth stress - SWth rest ) was present between viable and scar regions (1 0±0 3 versus -0 3 ±0 1, P<0 01; 1 0±0 3 versus -0 2±0 2, P<0 01). Conclusions. Dobutamine induced contractile reserve can be predicted in the regions of akinesia or dyskinesia at rest when systolic wall thickening was 1 0 mm during dobutamine stimulation.

关 键 词：myocardial  infarction inotropic  agents stress 

分 类 号：R817.42[医药卫生—影像医学与核医学]