艾滋病482例临床分析  

A clinical report on 482 AIDS cases

作　　者：李兴旺[1] 程荷荷 何云[3] 张福杰[1] 贾蔓红[2] 张家鹏[2] 仲英娜[4] 黄建东 崔维江 王磊 唐孟光[6] 刘惜年[6] 马义跃[7] 陈谐捷[7] 刁记年[7] 曹韵贞[8] 

机构地区：[1]北京地坛医院,100011 [2]云南省卫生防疫站 [3]郑州市第六人民医院 [4]新疆维吾尔自治区人民医院 [5]新疆伊梨友谊医院 [6]上海市传染病医院 [7]广州市第八人民医院 [8]中国预防医学科学院

出　　处：《中国抗感染化疗杂志》2001年第3期129-132,共4页Chinese Journal of Infection and Chemotherapy

摘　　要：目的 :了解我国艾滋病 (AIDS)患者的临床流行病学特点 ,自然病程及临床转归。方法 :汇集国内 6个地区的 4 82例AIDS患者的流行病学和临床资料 ,加以归纳总结。结果 :4 82例AIDS男女间的比例为 4∶1;其传播途径在云南、新疆主要为静脉注射毒品 ,河南为不洁献血和输血 ,而北京、上海、广州则主要为性途径传播 ;其性传播者的自然病程约为 8年 ,静脉注射毒品和经血感染者为 6年左右。临床症状以发热、消瘦、口腔和肺部感染等表现为主。常见的合并感染与文献报道类似。结论 :自 1985年发现第一例AIDS ,相当一部分人类免疫缺陷病毒 (HIV)感染者已进入AIDS期 ,本资料提示经血液途径感染者自然病程较经性途径感染者为短 ,我国HIV感染者中 70 .6%是静脉注射毒品者 ,提示及时预防感染、早期诊断 。To understand the epidemiological characteristics, natural courses and clinical features of AIDS patients in China. Methods:We collected and reviewed the epidemiological and clinical data of 482 AIDS cases in 6 cities and provinces. Results:The male∶female ratio was 4∶1 in these AIDS patients. The major route of HIV transmission was intravenoas drug injection in addicts in Yunnan and Xinjiang, blood transfusion in Henan, and homosexual or heterosexual activity in Beijing, Shanghai and Guangzhou. The natural course of developing AIDS was 8 years in average in individuals infected through sexual transmission, and approximately 6 years in patients infected through transfusion and drug use. The common manifestations were fever, wight loss, and oral or pulmonary infections. The complications were similar to those reported in the literatures. Conclusions:Since the first AIDS case reported in China in 1985, many HIV infected individuals have developed AIDS. The above data suggested that the natural course of AIDS was shorter in patients infected by transfusion than those through sexual behavior. Approximately 70.6% of HIV infection occurred in IV addict drug users. Therefore, easly diagaosis and implement of preventive measure are the key points in the comprehensive control of HIV/AIDS in China.

关 键 词：人类免疫缺陷病毒 艾滋病 传播途径 自然病程 并发症 临床流行病学 

分 类 号：R512.91[医药卫生—内科学]