螺旋结构与旋光方向(VI):手性4-取代[2.2]二聚二甲苯类化合物的螺旋结构与旋光方向  

Helical Structure and Optical Direction (Ⅵ): The Relationship Between Helical Structure and Optical Direction of Chiral 4-Substituted paracyclophane

作　　者：王莉[1] 尚卓镔[1] 张红[2] 解建仁[1] 邓并[1] 

机构地区：[1]山西大学化学化工学院,山西太原030006 [2]山西职工医学院,山西太原030012

出　　处：《山西大学学报（自然科学版）》2003年第4期334-338,共5页Journal of Shanxi University(Natural Science Edition)

基　　金：山西省归国留学人员基金

摘　　要：为了扩展我们的理论成果 ,现选取手性旋光的 4 -取代 [2 .2 ]二聚二甲苯类化合物 {其 CA命名为 5 -取代三环 [8.2 .2 .2 4 ,7]十六碳 - 4 ,6 ,10 ,12 ,13,15 -六烯 }作为螺旋结构与旋光方向研究的第六个序列 .通过构象分析和依据螺旋判定规则 ,指定了模型分子的旋光方向 ,然后从文献中找出了 2 1个这类衍生物和它们的旋光值 .比较结果显示 ,R-构型 4 -取代 [2 .2 ]二聚二甲苯类衍生物净值螺旋性为负 ,所显示的旋光方向也为负 ;同理 ,S-构型类净值螺旋性为正 ,所显示的旋光方向也为正 。In order to extend our theoretical results,now we select chiroptical 4-substituted paracyclophane (the nomenclature in CA is 5-substituted tricyclo[8.2.2.2^(4,7)]hexadeca-4,6,10,12,13,15 hexaene) compounds as the sixth alignment of the study on helical structure and optical rotation.By the analysis of conformation and based on the 'Helix and Rules for Finding out Helical Segments', the optical rotation of the model paracyclophanes were first appointed.Then 21 derivatives of paracyclophane and their values of optical rotation were found out from the literatures.The comparative results show that the 4-substituted paracyclophane with R-configuration possess minus net helicity and they all display negative optical rotations. Moreover, those with S-configuration possess plus net helicity and they display the positive values of optical rotation. Theoretical analysis corresponds to the practical cases and all of these suggest our views is to be correct.

关 键 词：螺旋结构 旋光方向 4-取代[2.2]-聚二甲苯 构象分析 

分 类 号：O632.71[理学—高分子化学]