不明原因不育症患者的抗精子抗体分析  

Analysis of Antisperm Antibody in Patients with Infertility of Unknown Causes

作　　者：曹佐武[1] 

机构地区：[1]暨南大学生殖免疫研究中心,广东广州510632

出　　处：《医学临床研究》2003年第10期766-768,共3页Journal of Clinical Research

基　　金：国家自然科学基金 (No .30 2 71370 );广东省自然科学基金 (No .0 10 398)

摘　　要：目的分析不明原因不育患者血清中抗精子抗体的发生率。方法筛选不明原因不育夫妇病例 ,用ELISA检测不育患者血清中的抗精子抗体。结果患者血清共 15 3份 ,8份阳性 ,占 5 .2 3%,其中男性血清阳性率为 3.6 4%(2 / 5 5 ) ,女性血清阳性率为 6 .12 %(6 / 98) ,没有发现夫妻双方同时阳性的病例。结论不明原因不育患者的血清抗精子抗体发生率较低 ,而男性患者的阳性率比女性患者的阳性率更低。ObjectivesTo analyze the incidence of antisperm antibody in the sera of patients with infertility of unknown causes.MethodsInfertile couples with unknown causes were screened and their serum levels of antisperm antibody were detected by ELISA.ResultsEight out of 153 serum samples from these infertile couples showed positive reaction of antisperm antibody, with an incidence of 5.23% . The serum positive rates in male patients were 3.64% (2/55); whereas those in female patients was 6.12% (6/98). Infertile couples displaying coexisted positive reaction in both sides were not found.ConclusionLow incidence of antisperm antibody is detected in the sera of infertile patients with unknown causes, the positive rate in serum samples of male patient is further lower than that of female patients.

关 键 词：不明原因不育症 抗精子抗体 血清 检测 免疫学 

分 类 号：R711.6[医药卫生—妇产科学] R446.62[医药卫生—临床医学]