高原护肤霜的研制  

PREPARATION OF GAOYUAN SKIN CARE CREAM

作　　者：钟延强[1] 孙其荣[1] 蒋雪涛[1] 徐允璋[1] 沈有安[1] 柳正良[1] 

机构地区：[1]中国人民解放军第二军医大学药学院,上海200433

出　　处：《解放军药学学报》1999年第4期37-38,共2页Pharmaceutical Journal of Chinese People's Liberation Army

基　　金：总后勤部卫生部专项课题

摘　　要：目的：研究防晒制剂以对抗高原紫外线辐射，防止皮肤灼伤。方法：采用聚甲基氧硅烷为基质，ＯＰ为主要乳化剂，辅加水杨酸苯酯、ＶｉｔＥ、ＴｉＯ２ 等多种防晒、防裂成分，制备Ｏ／Ｗ 型高原护肤霜。结果：本品在３７℃放置３ 个月和－ ２０℃放置１ 个月，高原护肤霜剂的物理和化学性质良好。结论：抗紫外、刺激性和过敏性实验表明，高原护肤霜抗紫外作用与基质对照组间有非常显著差异（ Ｐ＜０ ．０１） ，无皮肤刺激性，一次性涂眼无刺激性，长期涂布皮肤无毒性和过敏反应发生。AIM To study the preparation of GaoYuan Skin Care Cream.METHODS It was specially prepared with OP Silicon,Salol,VitE,TiO 2 etc for use in the plateau environment.Test of antiultraviolet,acute toxicity,irritation and hypersensitivity were performed in mice,rabbits and guinea pigs.RESULTS Stabilization Tests demonstrated that the cream had a good physical and chemical stability.CONCLUSION The results showed that it was a safe and effective antiultraviolet cream.

关 键 词：高原护肤霜 紫外线 辐射作用 皮肤 

分 类 号：R986[医药卫生—药品]