4种喹诺酮类药物的荧光光谱研究  

Study on Fluorescence Spectra of Four Quinolones

作　　者：王莹[1] 李树伟[1] 吴雪梅[1] 邹勤[1] 廖显威[1] 

机构地区：[1]四川师范大学化学学院,四川成都610066

出　　处：《四川师范大学学报（自然科学版）》2003年第6期617-619,共3页Journal of Sichuan Normal University（Natural Science）

基　　金：四川省教育厅重点科研基金资助项目

摘　　要：采用量子化学半经验方法RHF/AM1、RHF/PM3,对荧光法测定的4种喹诺酮类药物进行构型优化,经振动分析,未出现虚频率,在此基础上用RHF/CIS方法分别计算了它们的荧光光谱,所得结果与实验值基本符合.The fluorescence spectra of the four quinolones have been studied. Geometric configurations of the four quinolones have been optimized by semiempirical methods RHF/AM1, RHF/PM3 of quantum chemistry. There is no imaginary frequency in vibrational analysis. Their fluorescence spectra have also been calculated by RHF/CIS. The results of calculation are essentially consistent with experimental values.

关 键 词：喹诺酮 荧光光谱 量子化学 

分 类 号：O657.3[理学—分析化学]