Hypertonic saline solution resuscitation in hemorrhagic shock dogs  

作　　者：蔡秀军 黄迪宇 牟一平 彭淑牖 

出　　处：《Chinese Journal of Traumatology》2002年第3期180-185,共6页中华创伤杂志（英文版）

摘　　要：Objective: To find out the optimal concentration, infusion rate and dosage of saline for resuscitation.Methods: Forty five dogs were used to establish hypovolemic shock models. The dogs were resuscitated with saline of different concentrations and different dosages under different infusion rates, and the resuscitation results were compared. Results: The best concentration was 7.5 %, the best rate of infusion 20 ml/min (a volume equivalent to 15% of the shed blood) and the best dosage 5.71 ml/kg. The method was effective for resuscitation, the mean arterial pressure (MAP) could be elevated to 89% of the baseline, and this MAP could be kept for more than one hour. Conclusions: Using 7.5 % sodium chloride solution equivalent to 15% of the shed blood at an infusion rate of 20 ml/min can achieve a best resuscitation result.

关 键 词：Shock  hemorrhagic Saline solution  hypertonic DOGS 

分 类 号：R602[医药卫生—外科学]