氟暴露对工人血清IL-8及NO含量的影响  

Effect of being Exposed to Fluoride on the Concentration of IL 8 and NO in Serum of Workers

作　　者：张海谋[1] 宋世震 陈荣安 郑红燕 

机构地区：[1]同济医科大学职业医学研究所,武汉430030

出　　处：《职业卫生与病伤》1999年第3期133-135,共3页Occupational Health and Damage

摘　　要：选取某铝厂工人６６ 人，观察血清氟、尿氟浓度，血清ＩＬ－ ８ 及ＮＯ含量变化情况。结果显示：和对照组比较，氟暴露组血清氟浓度和尿氟浓度明显增高；血清ＩＬ－ ８ 含量高工龄组升高，而低工龄组无变化；血清ＮＯ 含量低工龄组升高而高工龄组降低。提示机体染氟后通过各种正向或反向调节维持正常的免疫应答。其中ＩＬ－ ８ 及ＮＯ参与了复杂的免疫调节。workers from a certain aluminium plant were selected to study the changes of [F -]in serum and urine,IL 8 and NO contents in serum.The results showed that comparing with the control,of the exposure group,[F -]in serum and urine increased;IL 8 content in serum increased in high standing group,there no change in low standing group;NO content in serum incresed in low standing group and decreased in high standing group.It indicated that bodies maintained the normal immune response through positive or opposite immune regulation after being exposed to fluoride,IL 8 and NO all took part in this complicate course.

关 键 词：氟暴露 血清 IL-8 NO 作业工人 职业卫生 免疫应答 免疫调节因子 

分 类 号：R135.1[医药卫生—劳动卫生]