1999至2001年上海市抗抑郁药用量分析  

Antidepressants utilization analysis in Shanghai during 1999-2001

作　　者：顾之光[1] 季闽春[1] 耿晓芳[1] 杜文民[2] 

机构地区：[1]华东医院临床药理室,上海200040 [2]上海市药品不良反应监测中心,上海200040

出　　处：《中国临床药学杂志》2003年第6期352-355,共4页Chinese Journal of Clinical Pharmacy

摘　　要：目的 :了解上海市抗抑郁药的用药情况和发展趋势。方法 :利用上海市医院用药分析系统 (HPDIS)提供的上海市 4 7家医院 1999至 2 0 0 1年抗抑郁药用药信息。根据限定日剂量 (DDD)、DDD数 (DDDs)、购药金额 ,分析上海市 4 7家医院近 3a抗抑郁药的药物利用情况。结果 :上海市抗抑郁药总体利用情况呈逐年上升趋势。氟西汀是最常用的抗抑郁药 ,帕罗西汀次之 ,三环类抗抑郁药 (TCAs)用量明显下降 ,新型抗抑郁药初露端倪。结论 :上海市抗抑郁药用量呈上升趋势。选择性 5 HT再摄取抑制剂 (SSRIs)AIM:To estimate the trend of antidepressants utilization and development in Shanghai METHODS:The data of antidepressants consumption of 47 hospitals in Shanghai during 1999 2001 was obtained from hospital purchasing of drug information system(HPDIS) Based on defined daily dose(DDD),DDDs and costs,utilization of antidepressants was analyzed in the past 3 years RESULTS:Total antidepressants consumption increased annually Fluoxetine was in the first rank,paroxetine was in the second rank DDDs of tricyclic antidepressants(TCAs) were decreasing obviously New antidepressants had a low level of utilization CONCLUSION:Antidepressants consumption is increasing rapidly in Shanghai Selective serotonin reuptake inhibitors(SSRIs) are substituting for tricyclic antidepressants

关 键 词：上海市 抗抑郁药 用量分析 药物利用 

分 类 号：R969.3[医药卫生—药理学]