反相离子对色谱研究铝与儿茶酚胺的相互作用  

Study on Interaction between Aluminum and Catecholamine by Reversed- phase Ion- pair HPLC

作　　者：练鸿振[1] 戴翔[1] 邹公伟[1] 毕树平[1] 田笠卿[2] 

机构地区：[1]南京大学化学系,南京210093 [2]南京大学现代分析中心,南京210093

出　　处：《分析科学学报》2003年第5期419-420,共2页Journal of Analytical Science

基　　金：国家自然科学基金(No.20075011);南京大学现代分析中心测试基金

摘　　要：用反相离子对高效液相色谱法初步研究了铝与儿茶酚胺的相互作用。结果显示,去甲肾上腺素的峰高随加入铝的增加而线性下降,铝与去甲肾上腺素的配位比为1∶1。该项研究为进一步活体测定铝提供了一条新思路。Interaction between aluminum and catecholamine has been investigated preliminarily by reversed- phase ion- pair high performance liquid chromatography. It is found that the chromatographic peak area of noradrenaline linearly decreases with the increase of the concentration of aluminum added, and the complexing ratio of aluminum to noradrenaline is 1∶1. A new direction for further development of the ~ in vivo~ indirect determination of aluminum is provided in this paper.

关 键 词：反相离子 高效液相色谱 铝 儿茶酚胺 相互作用 

分 类 号：O614.31[理学—无机化学] O657.72[理学—化学]