5-羟色胺在碳纤维微电极上的电化学测定及伏安行为研究  

Study on the Electrochemistry of Serotonin at Carbon Fiber Microelectrodes

作　　者：刘辉[1] 孙佳[2] 刘灵芳[2] 冶保献[1] 

机构地区：[1]郑州大学化学系,郑州450052 [2]信息工程大学理学院,郑州450003

出　　处：《分析科学学报》2003年第5期470-471,共2页Journal of Analytical Science

基　　金：河南省自然科学基金(No.0211020400)

摘　　要：本文研究了5 羟色胺在Na2HPO4 KH2PO4(pH6.0)缓冲溶液中,于自制的碳纤维微电极上的伏安行为。在此缓冲溶液中5 羟色胺有一对氧化还原峰,峰电位分别为0.2V和0.4V。峰电流与5 羟色胺的浓度分别在4.0×10-6～4.0×10-5mol/L和5.0×10-6～5.0×10-5mol/L范围内呈良好的线性关系,检出限分别为4.70×10-6mol/L和1.76×10-6mol/L。同时利用多种电化学方法求出了动力学参数。The paper describes the electrochemistry behavior of serotonin at carbon fiber microeletrodes.In the phosphate buffer(pH 6.0),a diffusion- driven redox peaks of serotonin is obtained with the peak potentials of 0.4 V and 0.2 V,respectively (vs. SCE).Under the selected conditions with different pulse voltammetry,the peak currents are linear with serotonin concentration in the range of 5.0×10~ -6 ～5.0×10~ -5 mol/L with the detection limit of 1.96×10~ -6 mol/L(oxidation reaction) and 4.0×10~ -6 ～4.0×10~ -5 mol/L with detection limit of 4.70×10~ -6 mol/L (reduction reaction) respectively.

关 键 词：5-羟色胺 碳纤维微电极 电化学 测定 伏安行为 示差脉冲伏安法 单胺类神经递质 

分 类 号：Q421[生物学—神经生物学]