DNA与RNA谁是主角?  

DNA and RNA Which Plays the Lead?

作　　者：朱圣庚[1] 

机构地区：[1]北京大学生命科学学院,北京100871

出　　处：《北京大学学报（自然科学版）》2003年第6期770-774,共5页Acta Scientiarum Naturalium Universitatis Pekinensis

摘　　要：DNA与RNA相伴而生 ,是一对孪生分子。生命起源最早出现可能是“核酸世界” ,DNA与RNA是后来分化产生的。在当今生命系统中 ,DNA、RNA和蛋白质起着决定的作用 ,成为生命系统中的三驾马车。RNA干扰的发现表明 ,生物基因表型的变化是受RNA控制的。RNA转录后复杂的加工过程反映了RNA的进化历程。因此 ,重新认识RNA已成为当前生命科学亟待解决的问题。DNA and RNA exist together and they can be a pair of twin molecules. It seems that the earliest era of life origin is referred to as the “nucleic acid world”, a fterwards DNA and RNA were generated separately by differentiation. In th e modern life system, DNA, RNA and protein together play a decisive role, and th e system is a three-horse-drawn carriage. The discovery of RNA interference sh ow s that the change of phenotype of the gene can be controlled by RNA. The posttra nscriptional processing of RNA is probably a reflection of the procedure of RNA evolution. Therefore, it is an urgent task to understand RNA again in life scien ces.

关 键 词：孪生分子 核酸世界 RNA干扰 生命的进化 

分 类 号：Q52[生物学—生物化学]