Crystal Structure of 10-(2',5'-Dimethoxybenzylidene) Anthrone  

作　　者：胡惟孝 徐端钧 周卫 孙雅泉 

机构地区：[1]Institute of Pharmaceutical Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China [2]Department of Chemistry, Zhejiang University, Hangzhou, Zhejiang 310028, China

出　　处：《Chinese Journal of Structural Chemistry》2003年第6期653-656,共4页结构化学（英文）

基　　金：Project supported by the Zhejiang Natural Science Foundation (No. 200016)

摘　　要：The anthrone reacts with 2,5-dimethoxybenzaldehyde under base catalyst to afford the title compound (C23H18O3, Mr = 342.37). The crystal belongs to monoclinic, space group P21/c with a = 13.046(4), b = 8.937(2), c = 15.549(4) ? b = 106.52(3), V = 1738.1(8) 3, Z = 4, Dc = 1.308 g/cm3, m = 0.086 mm-1 and F(000) = 720. The final R = 0.0331 and wR = 0.0850. The results show that the two phenyl rings of the anthrone fragment are not coplanar, but with a dihedral angle of 157.92. The middle ring of the anthrone moiety appears asymmetric boat conformation, while the 2,5-dimethoxyphenyl ring is restricted rotation. Therefore they exist in two optically active forms which are symmetrical glidingly.The anthrone reacts with 2,5-dimethoxybenzaldehyde under base catalyst to afford the title compound (C23H18O3, Mr = 342.37). The crystal belongs to monoclinic, space group P21/c with a = 13.046(4), b = 8.937(2), c = 15.549(4) ? b = 106.52(3), V = 1738.1(8) 3, Z = 4, Dc = 1.308 g/cm3, m = 0.086 mm-1 and F(000) = 720. The final R = 0.0331 and wR = 0.0850. The results show that the two phenyl rings of the anthrone fragment are not coplanar, but with a dihedral angle of 157.92. The middle ring of the anthrone moiety appears asymmetric boat conformation, while the 2,5-dimethoxyphenyl ring is restricted rotation. Therefore they exist in two optically active forms which are symmetrical glidingly.

关 键 词：ANTHRONE 10-(2 5-dimethoxybenzylidene) anthrone crystal structure SYNTHESIS 

分 类 号：R979.1[医药卫生—药品] R914.4[医药卫生—药学]