人免疫球蛋白稳定性的两种试验方法结果比较  

Comparing the results of two methods of stabiliy test for human immunoglobulin

作　　者：刘燕[1] 李振平[1] 周耀东[1] 常娅莉[1] 杨庆梅[1] 

机构地区：[1]兰州生物制品研究所,兰州730046

出　　处：《微生物学免疫学进展》2003年第4期50-53,共4页Progress In Microbiology and Immunology

摘　　要：通过检测人免疫球蛋白制品中抗 HBs含量的变化情况 ,采用留样观察法和加速试验法对不同温度条件下的人免疫球蛋白有效期进行预测。结果表明 ,与常规留样观察法相比 ,加速实验法推测出的药物有效期出现一定的偏差 ,所以应用于人免疫球蛋白稳定性观察仅能提供参考性数据。The expiration of human immunoglobulin stored at different temperature was respectively observed by means of detection of anti HBs titer. The results indicated that there was deviation between the routine regulation method and acceleration test. It drawn a conclusion that the expiration of Human immunoglobulin should be determined based on data of routine test other than acceleration test by using samples stored at different temprature.

关 键 词：人免疫球蛋白 稳定性试验 抗-HBS 含量 留样观察法 加速试验法 

分 类 号：R392[医药卫生—免疫学]