聚合物材料表面纳米条纹对生物细胞生长的影响  

Influence of Nanostructured Polymer Surface on Cell Growth

作　　者：陆海伟[1] 路庆华[1] 陈万涛[2] 徐宏杰[1] 印杰[1] 

机构地区：[1]上海交通大学化学化工学院 [2]上海第二医科大学附属第九人民医院口腔颌面外科口外肿瘤生物实验室,上海200011

出　　处：《高等学校化学学报》2003年第12期2324-2326,共3页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金 (批准号 :2 0 0 0 40 0 6;60 0 870 0 1);上海市人民政府科技委员会基金 (纳米专项 ) (批准号 :0 2 49nm0 3 7)资助

摘　　要：The nanogrooved surface of polystyrene(PS) petri-dishes was induced by an ultraviolet laser irradiation method. The influence of the surface nanostructure on the growth of the human tongue squamous cells carcinomas (HTSCC) was investigated. Cells cultured on laser-irradiated PS surface show an enhanced attachment and spreading in HTSCC cell culture test, and cell orientation was successfully controlled by selectively treating the PS surface. We also prove that the nanostructures on polymer surface improved the cell attachment and spreading.The nanogrooved surface of polystyrene(PS) petri-dishes was induced by an ultraviolet laser irradiation method. The influence of the surface nanostructure on the growth of the human tongue squamous cells carcinomas (HTSCC) was investigated. Cells cultured on laser-irradiated PS surface show an enhanced attachment and spreading in HTSCC cell culture test, and cell orientation was successfully controlled by selectively treating the PS surface. We also prove that the nanostructures on polymer surface improved the cell attachment and spreading.

关 键 词：聚合物材料 生物材料 细胞培养 纳米条纹 细胞生长 化学表面改性 紫外光激光诱导法 

分 类 号：R318.08[医药卫生—生物医学工程]