甲亢患者餐后2h血清CG检测的临床意义  

The Significance of the Serum CG Level of 2 Hours After Meal in Hyperthyroid Patients

作　　者：王虹[1] 刘明凤[1] 张爱华[1] 卓连坤[1] 白振莲[1] 宋庆璋[1] 

机构地区：[1]山东莱芜市人民医院核医学科,山东莱芜271100

出　　处：《标记免疫分析与临床》2003年第4期218-220,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：本文为了观察不同病程甲亢患者肝细胞损害情况 ,对 1 32例甲亢患者按病程分 3组 ,以 5 0名正常人作为对照组。用RIA法检测空腹和餐后 2h血清CG水平。结果显示 :病程在 0 .5年以内患者空腹、餐后 2h血清CG水平与对照组无显著差异 (P >0 .0 5 ) ;病程在 0 .5 - 2年患者 ,餐后 2h血清CG水平高于对照组 (P <0 .0 1 ) ,空腹血清CG水平无显著差异 (P >0 .0 5 ) ;病程在 2年以上患者空腹、餐后 2h血清CG水平均增高 (P <0 .0 1 ,P <0 .0 0 1 ) ,且餐后 2h血清CG明显增高 (P <0 .0 0 1 )。结果提示 :检测餐后 2h血清CG水平 ,对了解甲亢患者肝细胞损害比空腹CG更为敏感 。To observe the liver condition of hyperthyroid patients with different course of disease, the levels of serum CG over night fasting and of 2 hours after meal in 132 hyperthroid patients and 50 normal persons were measured by RIA.Hyperthroid patients were divided into 3 groups by their different coiurse of disease.For normal persons and the group whose course of disease within half year there was no significant difference in CG levels of fasting and 2 hours after meal.For the group whose course of disease in period of 0.5-2 years the CG level of 2 hours after meal were over the normal range( P <0.01), but no differnece was found in CG level of fasting.For the group whose course of disease over 2 years, the CG levels of fasting and 2 hours after meal were all over the normal range( P <0.01, P <0.001), CG level of the 2 hours after meal was much higher.The results suggested that CG level measured 2 hours after meal was more sensitive than that after over night fasting in hyperthyroid patients with hepatocellular damage, and the damage degree has paralled to their courses of disease.

关 键 词：甘胆酸 甲亢 放射免疫分析 

分 类 号：R581.1[医药卫生—内分泌]