枸橼酸西地那非的电位滴定  

Potentiometry analysis of sildenafil citrate

作　　者：罗三来[1] 谭载友[1] 

机构地区：[1]广东药学院物理化学教研室,广东广州510240

出　　处：《广东药学院学报》2003年第4期312-313,324,共3页Academic Journal of Guangdong College of Pharmacy

摘　　要：目的 :寻找一种简便、准确的枸橼酸西地那非含量测定方法。方法 :使用电位滴定法对枸橼酸西地那非精制品含量进行测定。使用溶剂为醋酸和醋酸酐。结果 :滴定终点明确 ,精度较高。结论 :该方法成本低 。Objective:To find a simple and accurate method for the determination of content of sildenafil citrate. Method: Potentiometry was applied. Acetic acid glacial was used as main solvent and acetic anthydride was used as solubilizing agent. Result: The recovery rate was 100.5%. Conclusion: This method is comparatively accurate.

关 键 词：枸橼酸西地那非 电位滴定 醋酸 醋酸酐 

分 类 号：R927.2[医药卫生—药学]