复方木鸡冲剂治疗乙型肝炎肝硬变临床研究  

Clinical Observation on Fufang Muji Chongji in Treatment of Chronic Hepatitis B and Cirrhosis

作　　者：王丽[1] 

机构地区：[1]南京东南大学医学院附属徐州市第四人民医院,江苏徐州221009

出　　处：《辽宁中医杂志》2003年第12期988-989,共2页Liaoning Journal of Traditional Chinese Medicine

摘　　要：目的 :探讨复方木鸡冲剂抗肝纤维化和降甲胎蛋白 (AFP)作用。方法 :将慢性乙型肝炎肝硬变病人 89例随机分为木鸡组 (治疗组 )及对照组 ,分别于治疗前后检测肝纤维化血清学指标 (HA、PCⅢ、LN、Ⅳ -C)和血清AFP水平。结果 :治疗组治疗后肝纤维化指标和AFP水平均明显下降 ,与治疗组及对照组治疗后比较 ,差异显著(P <0 0 1)。结论 :复方木鸡冲剂有明显的抗肝纤维化和降低血AFP的作用。Objective:To study the clinical effect of Fufang Muji chongji on serum fibrosis marks hyaluronic acid(HA),procollagen typeⅢ(PCⅢ),collagen type Ⅳ(Ⅳ-c),Laminin(LN) and Alpha-fetoprotein(AFP)Levels in chronic hepatitis B and cirrhosis.Methods:89 patients with chronic hepatitis B and cirrhosis were divided into two groups:Muji group(45 patients)and the control group(44 patients).The levels of serum of fibrosis marks and AFP were proved before and after treatment in two groups.Results:The serum parameters of fibrosis and AFP all significantly changed after 3 mouths of treatment in muji groups(all P<0.01).Conclusion:Fufang muji chongji had the effects of autifibrosis and decrease AFP.

关 键 词：复方木鸡冲剂 慢性乙型肝炎肝硬变 AFP 肝纤维化 甲胎蛋白 中医药治疗 

分 类 号：R259.752[医药卫生—中西医结合]