药物不良事件的防范研究  

A Study of the Prevention of Adverse Drug Events in the Cardiovascular Departments

作　　者：迟丹怡[1] 王大猷[1] 李虹影 李中东[1] 时颖华[1] 王宏图[1] 钟明康[1] 

机构地区：[1]复旦大学附属华山医院药剂科,上海200040 [2]上海市吴淞医院药剂科

出　　处：《药物流行病学杂志》2003年第6期301-303,共3页Chinese Journal of Pharmacoepidemiology

摘　　要：目的 :探讨心内科病房药物不良事件 (ADE)的防范特征。方法 :由药师深入心内科病房 ,集中监测药物不良事件。主要监测内容是药物不良事件的存在与否 ,可否防范及严重程度。结果 :5个月研究期间共鉴定ADE 64次 ,其中 2 8%可以防范。在重度ADE中 ,50 .0 %可防范 ;在中度ADE中 ,3 3 .3 %可防范 ;在轻度ADE中 ,可防范的比例最少 ,为 13 .6%。结论 :药物不良事件中有相当一部分可以防范 ,而且越是严重的ADE就越有可能被防范。Objective: To study the prevention of adverse drug events (ADE) in the cardiovascular depar tments.Methods: Pharmacists participated in the clinical drug therapy in the cardiovascular ward s in a tertiary hospital, intensively sur veying ADEs. The main measurements were presence, preventability and severity of an ADE.Result: There were 64 identified ADE, among which 28% were preventable. Of the severe AD Es, 50.0% were preventable; of the moderate ADEs, 33.3% were preventable; of the mild ADEs, 13.6% were preventable. Conclusion: The adverse drug events were common and often preventable in the cardiovascular wards, and the serious ADEs were more likely to be preventable. Some strategies should be taken to prevent ADEs.

关 键 词：药物不良事件 合理用药 心内科病房 心血管疾病 心血管药物 

分 类 号：R969.3[医药卫生—药理学]