黄参膏对晚期肝癌患者生活质量的影响  

Effect of Huangshen Electuary on the Living Qualityof Advanced Hepatic Cancer Patients

作　　者：甘爱华[1] 许岸高[1] 凌红[1] 陈惠新[1] 张育明[1] 童志勇[1] 徐永成[1] 

机构地区：[1]广东省惠州市中心人民医院消化科,惠州516001

出　　处：《中国中西医结合消化杂志》2003年第6期344-346,共3页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

摘　　要：目的 :研究黄参膏对晚期肝癌患者生活质量的影响。方法 :12 5例晚期肝癌患者随机分为两组 ,两组均给予一般对症、护肝治疗 ;治疗组加口服黄参膏 2 0 m l,3次 / d,2个月为 1个疗程 ,记录治疗前后两组患者的肿瘤直径、静脉癌栓、远处转移、行为状态评分 (采用 Karnofsky评分标准 )及生存时间。结果 :治疗组服药 2个月后肿瘤直径较治疗前无明显变化 (P>0 .0 5 ) ,对照组 2个月后肿瘤直径明显增大 (P<0 .0 1) ;合并静脉癌栓及远处转移例数对照组明显多于治疗组 (均 P<0 .0 5 ) ;治疗组行为状态评分较用药前明显增高 (P<0 .0 1) ,对照组明显下降(P<0 .0 1) ;患者生存时间治疗组较对照组明显延长 (P<0 .0 1)。结论 :黄参膏可能是一种较为理想的中药抗肿瘤制剂 ,能提高晚期肝癌患者的生活质量。Objective:To study the effect of Huangshen electuary(HE) on the living quality of advanced hepatic cancer patients. Methods:125 patients with advanced hepatic cancer were divided into treatment group and control group. The former was given HE for two months. Tumor diameters,tumor emboli in veins,distant metastasis,behavior scales (evaluated by Karnofsky scale) and survival time(before and after the treatment were observed).Results: There was no significant difference in tumor diameter of the treatment group after two months ( P >0.05),while the tumor diameter enlarged obviously in the control group ( P <0.01). The cases complicated with tumor emboli in veins and distant metastasis in the control group were more than that in the treatment group ( P <0.05 respectively ). The behavior scales of the treatment group ascended( P <0.01) and survival time was obviously prolonged ( P <0.01) compared to these of the control group in which the behavior scales descended significantly ( P <0.01). Conclusion:HE was a safe and effective anti-tumor medicine,which could improve the living quality of advanced hepatic cancer patients.

关 键 词：黄参膏 晚期肝癌 生活质量 中医药疗法 中药抗肿瘤制剂 

分 类 号：R286.91[医药卫生—中药学] R273.57[医药卫生—中医学]