细菌耐药机制及临床对策  

Mechanism and Clinical Observation of Bacterial Drug Resistance

作　　者：苗海霞[1] 李宗瑜 

机构地区：[1]黑龙江省医学会,黑龙江哈尔滨150001 [2]哈尔滨市第五医院,黑龙江哈尔滨150040

出　　处：《黑龙江医学》2003年第11期806-809,共4页Heilongjiang Medical Journal

摘　　要：细菌耐药已经成为一个全球性共同关注的问题。因此 ,对于临床医生来说 ,必须掌握细菌的耐药机制 ,依据抗菌药物的抗菌作用给药。本文探讨了细菌耐药性的机制、分类、耐药的趋势及特点 ,以便制定出相应的临床对策和设计合理的给药方案 ,以达到良好的抗菌作用 ,降低不良反应发生率 ,同时提高患者的顺应性 ,减轻患者的医疗负担。There has been a global acknowledgment of the serve problem of bacterial drug resistance, and the drug-abuse of antibiotics has become a unsolvable problem for a long period of time. The waste of the health resource and the toxic and side effects caused by the drug-abuse hurts people deeply. A conclusion from some scholars showed that the outbreak of SARS in China may have something to do with the drug-abuse of antibiotics. So it's important for the clinical doctors to know the mechanism of bacterial drug resistance and use the essential drugs based on their action. This essay explored the mechanism and classification of bacterial drug resistance, the tendency and specificity in order to order relative clinical solution, reasonable drug using scheme, obtaining perfect antibiotic action, decreasing side effects, elevating the compliance of patients, lessening the medical burden.

关 键 词：药理学 细菌耐药机制 对策 抗菌药物 

分 类 号：R978.1[医药卫生—药品]