N-(糖基硫代亚脲基)-芳基硫代磷酰胺芳基酯的合成  

Synthesis of aryl N-(glycosylthioureylene)-arylthiophosphoramidates

作　　者：曹玲华[1] 周传健[1] 

机构地区：[1]新疆大学化学化工学院

出　　处：《化学研究与应用》2003年第6期841-843,共3页Chemical Research and Application

基　　金：国家自然科学基金(29962002);南开大学元素有机化学国家重点实验室开放基金资助项目

摘　　要：The Reaction of arylatrloxythiophosphoric hydrazide 2a～2d with glycosyl isothiocyanates 3a～3d gave the corresponding aryl N-（glycosylthioureylene）-arylthiophosphoramidates 4a～4d,5a～5d,6a～6d,7a～7d.The resulted compounds contained glycosylthioureylene and thiophosphoric amide fragments.The glycosyl isothiocyanates 3a～3d were prepared by the reaction of α-D-glycosyl bromides with Pb（SCN）2.The biologic activities of the representative compounds were studied.The Reaction of arylatrloxythiophosphoric hydrazide 2a～2d with glycosyl isothiocyanates 3a～3d gave the corresponding aryl N-(glycosylthioureylene)-arylthiophosphoramidates 4a～4d,5a～5d,6a～6d,7a～7d.The resulted compounds contained glycosylthioureylene and thiophosphoric amide fragments.The glycosyl isothiocyanates 3a～3d were prepared by the reaction of α-D-glycosyl bromides with Pb(SCN)_2.The biologic activities of the representative compounds were studied.

关 键 词：N-(糖基硫代亚脲基)-芳基硫代磷酰胺芳基酯 合成 硫代磷酰肼 结构分析 

分 类 号：O627.51[理学—有机化学]