豆甾醇和β-谷甾醇在环己酮和正戊醇中的溶解特性研究  

Studies on the Solubility of Stigmasterol and β-Sitosterol in Cyclohexanone and n-pentanol

作　　者：许文林[1] 黄一波[1] 钱俊红[1] 吴君峰[1] 

机构地区：[1]扬州大学化学化工学院,江苏扬州225002

出　　处：《高校化学工程学报》2003年第6期707-710,共4页Journal of Chemical Engineering of Chinese Universities

基　　金：国家自然科学基金(20176047);江苏省教育厅自然科学基金(99KJB150007);江苏省"青蓝工程"跨世纪学术带头人基金资助项目。

摘　　要：实验测定了豆甾醇和b -谷甾醇在环己酮和正戊醇为溶剂中不同温度下的溶解特性以及豆甾醇/b-谷甾醇/环己酮(正戊醇)三组分体系相图。实验结果表明,在相同条件下,b-谷甾醇在上述两种溶剂中的溶解度比豆甾醇的大,且在环己酮中溶解度随温度的变化比豆甾醇的变化大。同时探讨了以正戊醇和环己酮为溶剂,用重结晶法从精制植物甾醇中分离豆甾醇和b -谷甾醇的方法,并用红外和紫外光谱法定量分析了提纯产物中豆甾醇和b-谷甾醇的含量。The characteristics of the solubility of stigmasterol and b-sitosterol in a solvent of cyclohexanone or n-pentanol at different temperatures and the phase diagram of stigmasterol /b-sitosterol / cyclohexanone (or n-pentanol) under room temperature were determined. The experimental results show that the solubility of b-sitosterol in n-pentanol or cyclohexanone is larger than that of stigmasterol in the same solvent at the same condition, and that the solubility of b-sitosterol increases much faster with temperature in cyclohexanone than that of stigmasterol. The recrystallization for separating and purifying stigmasterol and b-sitosterol from phytosterol using n-pentanol or cyclohexanone as a solvent was studied. The content of stigmasterol and b-sitosterol in the crystal product was analyzed by IR and UV spectra motheds.

关 键 词：豆甾醇 Β-谷甾醇 植物甾醇 溶解特性 重结晶 分离 

分 类 号：O629.21[理学—有机化学] O645.12[理学—化学]