甲基取代的手性环酯化合物的螺旋结构与旋光性分析  

Studies on the Helical Structure and Optical Rotation of Methyl Substituted Chiral Cyclic Ester Compounds

作　　者：冯锋[1] 

机构地区：[1]雁北师范学院化学系,大同037000

出　　处：《高等学校化学学报》2004年第1期60-62,共3页Chemical Journal of Chinese Universities

基　　金：山西省自然科学基金 (批准号 :2 0 0 110 2 4);山西省高科技开发研究基金 (批准号 :2 0 2 6)资助

摘　　要：利用螺旋片段判定规则 ,结合 X射线衍射结构图及模型结构 ,对 4个大环酯类化合物及甲基取代产物的螺旋结构与旋光性进行了定量分析 ,检测结果证明了理论分析的正确性 ;对旋光值变化规律给予了合理解释 .Four cyclic esters(1—4) and four cyclic esters substituted by methyl(5—8) were synthesized and their values of optical rotation were determined by polarimeter. The relationships of their optical active behavior and helical structure were investigated with the Rules Finding out Helical Segment combining X-ray structure image and its model structure. The variation of optical rotation value was analyzed. The experimental results accord with the quantitative analysis. It is proved that the optical ratation of compound is determined by the net optical value of the molecule and the Rules Finding Out Helical Segment can be applied to the analysis of the chiral cyclic ester.

关 键 词：螺旋结构 螺旋片段判定规则 旋光性 手性环酯化合物 光学活性 立体化学 

分 类 号：O624.5[理学—有机化学] O621.22[理学—化学]