连续性静脉-静脉血液透析治疗重型HFRS肾功能衰竭  

Treatment of Renal Failure by Continuous Vein-vein Hemodialysis in Patients with Severe Hemorrhagic Fever Renal Syndrome

作　　者：邓红[1] 李小燕[1] 赵婕[1] 刘拉羊[1] 吕芳玲[1] 李谦[1] 

机构地区：[1]西安交通大学第二医院传染科,陕西西安710004

出　　处：《医学临床研究》2003年第11期843-845,共3页Journal of Clinical Research

摘　　要：目的探讨连续性静脉 -静脉血液透析 (CVVHD)治疗重型肾综合征出血热 (HFRS)肾功能衰竭的疗效。方法4 8例重型HFRS少尿期患者随机分为两组 ,CVVHD治疗组 2 8例 ,间歇性血液透析 (IHD)治疗 2 0例作为对照组 ,评判两组疗效 ,比较治疗中的不良反应发生率。结果治疗组在改善临床症状、促进肾功能恢复、缩短病程方面明显优于对照组。两组在发生不良反应及并发症方面差异有显著性。治疗组出现不良反应为 0例 ,并发症为 3例 ;对照组发生各种不良反应 12例 ,出现并发症 15例。结论在治疗重型HFRS少尿期肾功能衰竭中 ,CVVHD较IHD疗效好 ,可缩短病程 ,减少并发症 ,提高治愈率。ObjectivesTo explore the therapeutic efficacy of continuous vein-vein hemodialysis (CVVHD) for treatment of renal failure in patients with severe hemorrhagic fever renal syndrome (HFRS).MethodsForty-eight patients with severe HFRS in oliguria stage were randomly divided into two groups: (1)Treated group, 28 patients were treated with CVVHD; (2) Control group, 20 patients were treated with intermittent hemodialysis (IHD).The therapeutic efficacy in both groups was evaluated and their rates of adverse reaction during treatment were compared.ResultsThe therapeutic efficacy of treated group was distinctly better than that of control group in improving the clinical symptoms, promoting the recovery of renal function and shortening of disease course. Significant difference in adverse reactions and complications existed between both groups. Adverse reaction and complication in treated group were 0 and 3 cases respectively, versus 12 and 15 cases in the control group.ConclusionFor patients with severe HFRS in oliguria stage, CVVHD may be better than IHD to keep the electrolyte and acid-base balance, shorten the disease course, decrease the complications and to get a higher cure rate.

关 键 词：连续性静脉-静脉血液透析 治疗 重型HFRS 肾功能衰竭 重型肾综合征出血热 不良反应 

分 类 号：R692.5[医药卫生—泌尿科学] R512.8[医药卫生—外科学]