562名22～30岁志愿者精液质量的流行病学研究  

Epidemiological study on semen quality of 562 volunteers aged 22-30

作　　者：武俊青[1] 杨秋英[2] 陶建国[2] 李文英[2] 高尔生[2] 薄立伟 李玉仙 郭健 姚康寿 陆卫群 陈路 

机构地区：[1]复旦大学上海医学院 [2]上海市计划生育科学研究所 [3]河南省计划生育研究所 [4]河北省计划生育研究所 [5]山西省计划生育研究所 [6]浙江省计划生育研究所 [7]贵州省计划生育研究所 [8]青岛计划生育研究所

出　　处：《中华流行病学杂志》2004年第1期44-48,共5页Chinese Journal of Epidemiology

基　　金：上海市计划生育委员会基金资助项目(99JG01)

摘　　要：目的 分析中国年轻男性精液质量的地区性差别及影响因素。方法 研究对象来自全国7省(市)志愿者共562名,对合格者进行两次精液检查,质量测定指标有:精液量、黏稠度、液化时间、精液酸碱度、精子密度、活动精子百分比、畸形率等。结果 本项研究的结果显示,精液质量指标精液量、精子密度、精子前向运动率、精子存活率、正常形态精子百分率、精子总数在7省(市)之间差异均有统计学意义(P<0.05)。精液量以山西省自愿者最高(2.95 ml),河南最低(2.29 ml),其差值达28.82％。精子密度几何均数以贵州(36.27×106/ml)最低,山东(42.52×106/ml)其次,河北(74.77×106/ml)最高,河北和贵州的相差达一倍以上。精子前向运动率以河南最低(44.40％),其次为河北(51.88％)和浙江(52.88％),最高的是上海(76.50％)和山西(75.24％),其最高和最低值相差达72.30％。精子存活率最高的是上海(85.89％),最低的是河南(72.35％),其相差达18.71％。精子正常形态率以河北最低(68.45％),最高的是贵州(88.06％),相差达28.65％。精子总数的几何均数河北最高(204.23×106/ml),贵州最低(77.69×106/ml),相差达近二倍。方差分析及其两两比较的结果提示精液质量的一些指标在不同省(市)之间是有差别的。结论Objective This study is to understand the differenc of semen guality among the different areas and the related factors. Methods Five hundren and sixty-two people were under from seven provinces. Results Results showed that the quantity and density of semen, the rate of moving forward semen, livability, percent age of normal formed semen and the total number of semen were statistically different among the seven areas. The difference was ranged as 28.82% , with the highest 2.95 ml in Shanxi province and the lowest 2.29 ml in Henan province. Geometric mean of semen density was found the lowest 36.27×106/ml in Guizhou province, next to it was 42.52×106/ml in Shandong province and the highest was 74.77×106/ml in Hebei province. The percent age with forward progression of serm was seen the lowest 44.40% in Henan province, followed by 51.88% in Hebei province and 52.88% in Zhejiang provice and the highest were 76.50% in Shanghai, 75.24% in Shanxi province, with a range of 72.30% . The highest semen viability was 85.89% in Shanghai, while the lowest 72.35% in Henan,with a range of 18.71%. Normal sperm morphology was seen the lowest 68.45% in Hebei province, with the highest 88.06% in Guizhou province, and the range was 28.65%. The geometric mean of total sperm count was seen the highest 204.23×106/ml in Hebei province and the lowest 77.69×106/ml in Guizhou province. Results showed through analysis of variance that some indexes were different in some provinces. Conclusion The results indicated that the semen quality was different in different regions in China and its influential factors may be region and geography enviroment.

关 键 词：志愿者 精液质量 流行病学 地区差异 影响因素 精液量 黏稠度 液化时间 

分 类 号：R181.3[医药卫生—流行病学]