复方盐酸吗啉双胍注射液对大白鼠的亚慢性毒性试验  

Subchronic Toxic Test of Compound Hydrochloride Moroxydinum in Rats

作　　者：林雁春[1] 贾冬舒[2] 陈威 刘晓华[1] 

机构地区：[1]吉林农业大学动物科技学院,吉林长春130118 [2]解放军军需大学军需工程系,吉林长春130062 [3]长春圣泰动物药业有限公司,吉林长春130032

出　　处：《吉林农业大学学报》2003年第5期575-577,共3页Journal of Jilin Agricultural University

基　　金：吉林省科技厅资助项目

摘　　要：以大白鼠为试验动物,对复方盐酸吗啉双胍注射液进行了亚慢性毒性试验。结果表明:应用0.25mg/kg剂量的复方盐酸吗啉双胍注射液,对大白鼠的生理活动、生理生化指标、主要组织器官无不良影响,说明该制荆未表现毒性,临床可推广应用。Rats were used to investigate the subchronic toxicity of compound hydrochloride moroxydinum. The results showed that injection of the drug at a dose of 0.25 mg/kg body weight had no harmful effect on physiological activities, physiological and biochemical index and main tissues and organs, indicating that the drug is safe and can be used in clinic practice.

关 键 词：复方盐酸吗啉双胍注射液 大白鼠 亚慢性毒性试验 剂量 生理活动 生理生化指标 

分 类 号：R978[医药卫生—药品]