一氧化氮、内皮素与高血压病相关性的研究  

Correlation among hypertension and endotheiins, nitrogen monoxide

作　　者：郑伯仁[1] 陈桦[1] 陈文旭[1] 

机构地区：[1]福州市第二医院心内科,福建福州350007

出　　处：《心血管康复医学杂志》2003年第6期497-498,共2页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:探讨高血压病患者血浆一氧化氮(NO)内皮素(ET)及NO/ET比值与血压的关系。方法:采用硝酸还原酶法和双抗体夹心法测定高血压病患者62例,健康对照组58例的血浆NO和ET浓度及其比值并作比较分析。结果:高血压病组血浆NO水平明显低于对照组,ET水平明显高于对照组,NO/ET值也较对照组明显降低,P均<0.01。结论:高血压病患者血浆NO水平降低,ET水平增高及NO/ET失衡与高血压病有显著的相关性。To explore the correlation among hypertension and endothelins (EH), nitrogen monoxide (NO). Methods: Endothelins, nitrogen monoxide were detected in 62 patients with hypertension and 58 normal controls. Results: The endothelins level of hypertension group increased than normal control group (P<0. 01), nitrogen monoxide level and NO/EH of hypertension group decreased than normal control (P<0. 01 all). Conclusion: Hypertension markedly correlation with endothelins. nitrogen monoxide level.

关 键 词：一氧化氮 内皮素 高血压病 N0 ET 血浆 

分 类 号：R544.1[医药卫生—心血管疾病]