甘氨酸葡萄糖络铜(Ⅱ)的合成,表征及对O_2^-·和DNA的作用  

Synthesis and Characterization of Glycine-Glucose with Copper (II) complex and Its Effect on O2~. and DNA

作　　者：刘小琴[1] 乐芝凤[2] 张香才[2] 

机构地区：[1]三峡大学医学院,湖北宜昌443003 [2]华中师范大学化学系,武汉430070

出　　处：《三峡大学学报（自然科学版）》2003年第6期571-573,共3页Journal of China Three Gorges University：Natural Sciences

摘　　要：合成了二甘氨酸葡萄糖络铜(Ⅱ),并进行了组成及结构研究.采用比色法和荧光法研究该化 合物对超氧阴离子自由基和DNA的作用.结果表明:二甘氨酸葡萄糖络铜(Ⅱ)配合物能显著抑制 超氧阴离子自由基的生成,并能与DNA有效的结合.The synthesis of glycine and D-glucose with copper (II)complex has been studied. This compound is characterized by elemental analysis, IR,US-Vis and ESR. Effect of the Cu-Gly2-Glu on O_2-.and DNA has been tested. The results show that the Cu-Gly2-Glu could inhibit the synthesis of O_-. markedly and could also combine with the salmon sperm DNA.

关 键 词：合成 氨基酸葡萄糖铜(Ⅱ)配合物 DNA 比色法 荧光法 

分 类 号：O625.62[理学—有机化学]