天然植物配方驱铅效果动物实验研究  

Animal experiment of natural plant preparation in elimination of lead

作　　者：葛宪民[1] 黄曙海[1] 陈晓琴[1] 潘瑞辉[1] 陈婷婷[1] 李羡筠[1] 韦国铭[1] 苏旭[1] 

机构地区：[1]广西职业病防治研究所,广西南宁530021

出　　处：《中国工业医学杂志》2003年第6期348-350,共3页Chinese Journal of Industrial Medicine

基　　金：广西基金资助项目 (桂科攻 0 1 4 30 4 8)

摘　　要：目的　通过动物实验观察天然植物配方驱铅效果 ,同时对配方进行大鼠喂养实验。方法　大鼠腹腔注射 0 2 %醋酸铅 ,隔天注射 1次 ,共 2 0天 (10次 ) ;连续 8周每天经口灌入天然植物配方悬液 ,动态检测大鼠尿铅含量。结果　从驱铅开始至结束 ,驱铅实验组尿铅含量明显高于阳性对照组 ;配方成分 3 0d大剂量喂养对动物无毒副作用 ;配方对大鼠血中微量元素没有影响。结论　该天然植物配方有明显的驱铅效果 ,且 3 0d连续喂养实验未发现血中微量元素丢失及其他毒副作用。Objective To explore the effect of a compound natural plant preparation on lead elimination in rats with lead poisoning.Method A rat experimental model with lead poisoning was established by intraperitoneal injection of lead acetate every other day for 20 days.Then,a compound natural plant preparation was instilled into their stomach daily for eight weeks.Urine level of lead was measured dynamically.Result Urine level of lead was significantly higher in rats with natural plant preparation than in control rats.No adverse effect was observed in rats with large dose of the preparation for 30 days.There was no effect of the preparation on blood level of trace element.Conclusion This compound natural plant preparation had obvious effect on elimination of lead from animal bodies without any adverse effect or loss of trace element.

关 键 词：天然植物 铅吸收 动物实验 铅中毒 治疗 

分 类 号：R135.11[医药卫生—劳动卫生]